Basal Cell Carcnoma Higher Risk Factors

Non melanoma skin cancer ---> Basal cell carcinoma ---> metastatic risk

These include the following factors:
Recurrent tumor

Anatomic location
High risk: central face, eyelid, eyebrow, periorbital, nose, lip, chin, mandible, temple, ear, in front or behind the ear, genitalia, hand and foot
Medium risk: cheeks, forehead, scalp, and neck
Low risk: trunk, extremity (excluding hand/foot)

Size
Lesions +6 mm on high-risk area
Lesions +10 mm on medium-risk area
Lesions +20 mm on low-risk area

Histologic subtype pattern
Aggressive growth (morpheaform, fibrosing, sclerosing, infiltrating)
Micronodular

Ill-defined clinical borders
Perineural invasion
Development in sites of prior radiation
Immunosuppression